Ultra-widefield Fundus Imaging: Clinical Applications and Future Developments

Posted on August 15th, 2016 by
optomap - A comprehensive review published in Retina describes how ultra-widefield (UWF) is evolving to become the standard of care imaging modality for many diseases and is finding new clinical and research applications such as for screening and telemedicine.

Over the past decade Optos has expanded the capability of its core ultra-widefield fundus imaging technology, and with that has come a widening number of clinical applications.

Ultra-widefield (UWF™) imaging technology – enabling the capture of a 200-degree view of the retina without dilation – gives ocular health practitioners imagery and diagnostic information that can’t be provided by conventional imaging methods. Starting with color (red and green) optomap imaging, Optos has systematically extended its UWF-based technology into a multi-modal platform that supports fundus autofluorescence (optomap af), fluorescein angiography (optomap fa) and indocyanine green angiography (optomap icg).

 

 

Optos has also been incorporating the latest developments in image processing, providing users with important diagnostic and treatment management tools. In its latest software release, Optos has incorporated an advanced, proven stereographic projection algorithm that corrects for peripheral image variations that occur when a spherical image is flattened.

 

Clinical Applications

 

While the most common use of UWF technology may be in the diagnosis and treatment of diabetic retinopathy (DR), optomap imaging is also being used for characterizing pediatric retinal disease; age-related macular degeneration (AMD); retinal breaks and tears; uveitis, ocular oncology; central serous chorioretinopathy (CSCR); retinal vein occlusion (RVO); and a growing list of other …
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August is Child Eye Health and Safety Month – How Optos Is Making a Difference

Posted on August 8th, 2016 by
Make sure your child’s regular eye exams include optomap!

Why did Prevent Blindness, a national organization dedicated to advocacy for healthy vision, choose August as Children’s Eye Health and Safety Month? The three-word answer — back to school. Common eye conditions such as astigmatism, hyperopia (farsightedness), and myopia (nearsightedness), can compromise a child’s ability to read, comprehend classroom materials, and participate in games and sports. Over time, this can result in poor performance in school and social difficulties. What are the numbers? Studies report that nine percent of children ages 5 to 17 are affected by myopia; 13 percent are affected with hyperopia; and more than 15 percent with astigmatism. With statistics like these, August is an ideal time to schedule annual eye exams as part of every back-to-school checklist.

But annual eye exams aren’t just for the back-to-school crowd. Children under the age of six can also have vision difficulties. This is of particular concern, as undiagnosed vision difficulties in younger children can lead to developmental delays, affecting visual-motor and even cognitive functions. Along with the astigmatism, myopia and hyperopia, children 6 and under are also at risk for amblyopia, or “lazy eye.” Affecting 2 percent of children aged 6 to 72 months, if untreated, amblyopia can lead to permanent …
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Unexpected Results When “Healthy” People are Examined With UWF Retinal Imaging  

Posted on August 1st, 2016 by
Unexpected Results When “Healthy” People are Examined with UWF Retinal Imaging

As medical communities around the globe work to make the transition from treating sickness to preventing it, it’s still not the norm for healthy, asymptotic individuals to receive routine screening exams.

 

 

Ocular health is no exception. How often do adults with 20/20 vision and no eye-related symptoms schedule themselves for an optometric exam? That’s especially of concern considering that a number of ocular diseases such as, diabetic retinopathy (DR)1, open angle glaucoma2, age-related macular degeneration (AMD)3, and degenerative retinoschisis4, may not present any symptoms during their initial phases. Early detection of these diseases can have a significant impact on courses of treatment and the probability of positive outcomes.

 

One illustration of how UWF™ (ultra-widefield) imaging can improve the early detection of eye disease are the results of what amounts to an inadvertent experiment in the screening of healthy individuals. Training for Optos users and new Optos technical employees involves hands-on familiarization and instruction on UWF imaging systems. Part of that involves trainees taking color optomap images of themselves.  These training exercises sometimes yield unexpected results:

 

— Chad, who joined Optos in 2013, is a single parent and at the time of his hire had no history of eye problems. Prior to coming to Optos his full schedule and absence …
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New Studies Begin to Define the Extent of Healthy Retinal Vasculature

Posted on July 25th, 2016 by

The widening use of ultra-widefield (UWF™) retinal imaging by ocular health practitioners is prompting researchers to address what appears to be a straightforward question: What’s normal? That is, now that UWF imaging is providing a more complete visualization of the peripheral retina, what is the physical extent of healthy retinal vasculature?

 

It’s not an academic question. On one level, baseline information about the extent and appearance of healthy retinal vasculature is an essential part of clinical practice. But more important, as practitioners use UWF to measure the extent of retinal pathology – for example, in estimating areas of ischemia in patients with diabetic retinopathy (DR) or retinal vein occlusion (RVO) – it’s critical to measure the portion of the retina that is affected. These estimates need to start with accepted measurements for normal, healthy retinal vasculature, one derived from statistically significant population studies and adjusted for any variations in age, sex, or other characteristics.

 

New research is giving first indications of the extent of healthy retinal vasculature as well as important population variations. This work is being enabled by recent advances in UWF image processing which allow optomap® fa (fluorescein angiography) images to be corrected for peripheral distortion. These new processing algorithms – a part of Optos ProView™ imaging software – create …
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ILUVIEN® Intravitreal Implant Verification Using Ultra-widefield Imaging

Posted on July 18th, 2016 by
ILUVIEN® Intravitreal Implant, Charles Mayron MD, FACS Capital Retina Associates PLLC

A recent report describes a unique, high-value application of ultra-widefield (UWF™) retinal imaging in the treatment of Diabetic Macular Edema, or DME.

 

 

There are over 400 million people1 worldwide afflicted with diabetes and the long-term incidence of DME in this population is estimated at twenty to forty percent2. UWF imaging is already impacting the diagnosis and treatment of DME as well as Diabetic Retinopathy (DR), which frequently precedes or is associated with DME. Ultra-widefield imaging is unique in that it visualizes a much larger area of the retina (200°, or over 80%) as compared to conventional techniques that may image 45° or less of the retina. By imaging the peripheral retina practitioners and researchers have shown they can more accurately measure the extent of diabetic retinopathy3 as well as better predict the risk of future progression4. UWF is also helping public health initiatives by enabling accurate and cost-effective screening for DR5.

 

This novel application of UWF imaging supports a relatively new therapy for DME.  While the standards for DME treatment are undergoing intense study6, corticosteroids are often prescribed if anti-VEGF medications fail to control the chronic inflammation associated with DME. These corticosteroids are administered by direct injection into the eye, a process that must …
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