How UWF Imaging is Improving the Management of Sickle Cell Retinopathy

Posted on September 23rd, 2016 by
Sickle Cell Retinopathy FA

Recent research suggests that patients suffering from various systemic disorders may have their disease state impacted by the addition of ultra-widefield (UWF™) retinal imaging to their examination.  New research has found that patients with sickle cell disease may benefit from UWF retinal imaging for the diagnosis and management of sickle cell retinopathy (SCR).





Sickle cell disease is an inherited disorder in which the body produces blood cells with abnormally formed hemoglobin. Symptoms include anemia, severe and chronic pain, infection, hypertension, hand and foot swelling, leg ulcers, and retinal vascular changes1. Sickle cell disease can also have an impact on vision. Sickle cell retinopathy mainly affects the peripheral retinal vasculature2 as the result of abnormal, sickle-shaped blood cells becoming trapped in the small blood vessels of the eye3. Non-proliferative SCR, characterized by retinal hemorrhage from superficial blood vessels, can cause loss of visual acuity. Proliferative SCR is marked by vascular occlusions that lead to localized ischemia, neovascularization, and in later stages blindness from vitreous hemorrhage or tractional retinal detachment. Patients with sickle cell disease are at varying degrees of risk of developing SCR, but those with the type SC or S-Thal hemoglobin genotypes are at significant risk for developing …

Ultra-widefield Fundus Imaging: Clinical Applications and Future Developments

Posted on August 15th, 2016 by
optomap - A comprehensive review published in Retina describes how ultra-widefield (UWF) is evolving to become the standard of care imaging modality for many diseases and is finding new clinical and research applications such as for screening and telemedicine.

Over the past decade Optos has expanded the capability of its core ultra-widefield fundus imaging technology, and with that has come a widening number of clinical applications.

Ultra-widefield (UWF™) imaging technology – enabling the capture of a 200-degree view of the retina without dilation – gives ocular health practitioners imagery and diagnostic information that can’t be provided by conventional imaging methods. Starting with color (red and green) optomap imaging, Optos has systematically extended its UWF-based technology into a multi-modal platform that supports fundus autofluorescence (optomap af), fluorescein angiography (optomap fa) and indocyanine green angiography (optomap icg).



Optos has also been incorporating the latest developments in image processing, providing users with important diagnostic and treatment management tools. In its latest software release, Optos has incorporated an advanced, proven stereographic projection algorithm that corrects for peripheral image variations that occur when a spherical image is flattened.


Clinical Applications


While the most common use of UWF technology may be in the diagnosis and treatment of diabetic retinopathy (DR), optomap imaging is also being used for characterizing pediatric retinal disease; age-related macular degeneration (AMD); retinal breaks and tears; uveitis, ocular oncology; central serous chorioretinopathy (CSCR); retinal vein occlusion (RVO); and a growing list of other …

August is Child Eye Health and Safety Month – How Optos Is Making a Difference

Posted on August 8th, 2016 by
Make sure your child’s regular eye exams include optomap!

Why did Prevent Blindness, a national organization dedicated to advocacy for healthy vision, choose August as Children’s Eye Health and Safety Month? The three-word answer — back to school. Common eye conditions such as astigmatism, hyperopia (farsightedness), and myopia (nearsightedness), can compromise a child’s ability to read, comprehend classroom materials, and participate in games and sports. Over time, this can result in poor performance in school and social difficulties. What are the numbers? Studies report that nine percent of children ages 5 to 17 are affected by myopia; 13 percent are affected with hyperopia; and more than 15 percent with astigmatism. With statistics like these, August is an ideal time to schedule annual eye exams as part of every back-to-school checklist.

But annual eye exams aren’t just for the back-to-school crowd. Children under the age of six can also have vision difficulties. This is of particular concern, as undiagnosed vision difficulties in younger children can lead to developmental delays, affecting visual-motor and even cognitive functions. Along with the astigmatism, myopia and hyperopia, children 6 and under are also at risk for amblyopia, or “lazy eye.” Affecting 2 percent of children aged 6 to 72 months, if untreated, amblyopia can lead to permanent …

Unexpected Results When “Healthy” People are Examined With UWF Retinal Imaging  

Posted on August 1st, 2016 by
Unexpected Results When “Healthy” People are Examined with UWF Retinal Imaging

As medical communities around the globe work to make the transition from treating sickness to preventing it, it’s still not the norm for healthy, asymptotic individuals to receive routine screening exams.



Ocular health is no exception. How often do adults with 20/20 vision and no eye-related symptoms schedule themselves for an optometric exam? That’s especially of concern considering that a number of ocular diseases such as, diabetic retinopathy (DR)1, open angle glaucoma2, age-related macular degeneration (AMD)3, and degenerative retinoschisis4, may not present any symptoms during their initial phases. Early detection of these diseases can have a significant impact on courses of treatment and the probability of positive outcomes.


One illustration of how UWF™ (ultra-widefield) imaging can improve the early detection of eye disease are the results of what amounts to an inadvertent experiment in the screening of healthy individuals. Training for Optos users and new Optos technical employees involves hands-on familiarization and instruction on UWF imaging systems. Part of that involves trainees taking color optomap images of themselves.  These training exercises sometimes yield unexpected results:


— Chad, who joined Optos in 2013, is a single parent and at the time of his hire had no history of eye problems. Prior to coming to Optos his full schedule and absence …

New Studies Begin to Define the Extent of Healthy Retinal Vasculature

Posted on July 25th, 2016 by

The widening use of ultra-widefield (UWF™) retinal imaging by ocular health practitioners is prompting researchers to address what appears to be a straightforward question: What’s normal? That is, now that UWF imaging is providing a more complete visualization of the peripheral retina, what is the physical extent of healthy retinal vasculature?


It’s not an academic question. On one level, baseline information about the extent and appearance of healthy retinal vasculature is an essential part of clinical practice. But more important, as practitioners use UWF to measure the extent of retinal pathology – for example, in estimating areas of ischemia in patients with diabetic retinopathy (DR) or retinal vein occlusion (RVO) – it’s critical to measure the portion of the retina that is affected. These estimates need to start with accepted measurements for normal, healthy retinal vasculature, one derived from statistically significant population studies and adjusted for any variations in age, sex, or other characteristics.


New research is giving first indications of the extent of healthy retinal vasculature as well as important population variations. This work is being enabled by recent advances in UWF image processing which allow optomap® fa (fluorescein angiography) images to be corrected for peripheral distortion. These new processing algorithms – a part of Optos ProView™ imaging software – create …